LIMITED-TIME OFFER: BUY 5 PROBES, PAY FOR 4! (ENDS DECEMBER 31, 2024)
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Petri Dish Probes

€500

Petri dish probes are compatible with Piuma and Chiaro nanoindenter.
Selection recommendations

Well Plate Probes

€500

Well plate probes are compatible with Pavone, Piuma and Chiaro nanoindenters. These probes are suitable for use with 6-, 12-, 24-, 48-, 96-well plates and other deep dishes.
Selection recommendations

Cuore Cardiac Cell Kit

€5.000

Includes the essential components* to generate 24 engineered heart tissues with Cuore and to perform functional contractility studies. The kit combines high-quality human iPSC-derived ventricular cardiomyocytes from Axol Bioscience (ax2558) with optimized culture media specifically validated for use in the Cuore platform.

Contents

  • 2 vials of human iPSC-derived ventricular cardiomyocytes (Axol ax2558) .  5 million cells per vial.
  • 3 bottles of Cardiomyocyte maintenance medium optimized for tissue formation and long-term culture
    • Volume: 500 mL basal medium + 10 mL supplement
    • Shipping conditions: Cool packs for the basal medium, dry ice for the supplement
    • Storage conditions: Store the basal medium at 4ºC and the supplement at -80º
  • Complete Quality Control package including Certificate of Analysis (CoA) 
*Please note that the execution of the protocol requires additional components and materials not included in this kit. Refer to the Cardiac Casting protocol for a full list.

Training Probes Package

€500

Five probes, available either in well plate or petri dish format, plus a hydrogel sample. These probes are ideal for training new users or experimenting with new protocols, eg. tip functionalization. Note that these probes are NOT calibrated, and available in a single stiffness and tip radius combination (2-7 N/m, est. radius 100 μm). Only suitable for qualitative measurements and training.
Selection recommendations

Optical Fiber Inspection & Cleaning Kit

€150

Kit for inspection and cleaning of optical fiber connectors used with Optics11 Life nanoindenters. Includes a fiber microscope, fiber cleaner, and E2000 opener. Intended for preventive maintenance and troubleshooting.
Selection recommendations

More about probes

Given a sample, the suitability of a probe stiffness/tip radius combination depends on its properties and test parameters such as indentation depth. To ensure optimal results, we suggest reviewing the literature for similar samples, and evaluating the probe choice with our probe calculator. You can find the spreadsheet in the customer package folder, located on the desktop of the computer that came with your nanoindenter. In case of doubt, do not hesitate to contact our support team through the contact form below.

More about probes

All our probes are pre-calibrated* and reusable force sensors compatible with the respective Optics11 Life Nanoindenters. The probes are cantilever-based with an optical-fiber interferometric readout and are manufactured at our headquarters in Amsterdam, the Netherlands.

Depending on the application, the spring constant of the probe can be chosen between 0.025 N/m and 50 N/m which can measure elastic modulus between 10Pa and 1GPa. The unique feature of our probes is the large cantilever bending (up to 20μm) which allows to measure stiffness values spanning up to 5 orders of magnitude with a single probe. Spherical (colloidal) glass tips mounted onto the cantilever can be chosen from 3 µm to 250 µm in radius to perform single indentations or indentation mapping at various depths/loads and resolutions.

*The exact specifications of the probes may differ slightly from the catalog value, typically within a range of 20%. Due to the probes’ ability to measure across several orders of magnitude, all probes within this range are compatible with the same samples. The uncertainty (k = 2) of the stiffness calibration is at most 5% (10% for 0.025 N/m probes) and the tip radius is measured to the nearest half-micrometer.

Sample type - tip radius recommendation

Single cells

3 µm
10 µm

2D monolayers

3 µm
10 µm

Hydrogels

25 µm
50 µm
100 µm
250 µm

Tissues

25 µm
50 µm
100 µm

Spheroids

3 µm
10 µm
25 µm
50 µm

Organoids

3 µm
10 µm
25 µm

Oocytes

10 µm
25 µm
50 µm

Sample stiffness - probe specification recommendation

Sample stiffness

Tip radius

Probe stiffness

10 Pa – 18 kPa
3 µm
10 µm
25 µm
0.025 N/m
200 Pa – 360 kPa
3 µm
10 µm
25 µm
50 µm
0.5 N/m
1.4 kPa – 2.5 MPa
3 µm
10 µm
25 µm
50 µm
3.5 N/m
18 kPa – 36 MPa
10 µm
25 µm
50 µm
50 N/m

Probe orders of 10+ probes may take longer than our standard 4-week lead time to fulfill. For a delivery estimate, contact our support team at support@optics11life.com or by filling out the contact form.

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